Why You’ll Love This Recipe

This casserole is quick to assemble, uses everyday pantry staples, and is an excellent way to use leftover or rotisserie chicken. The creamy chicken filling pairs perfectly with the crispy, buttery stuffing topping, creating a delicious combination of textures and flavors. It can also be made ahead of time and freezes well for future meals.

Ingredients

(Tip: You’ll find the full list of ingredients and measurements in the recipe card below.)

Cooked chicken breast, shredded or diced
Herb-seasoned stuffing mix
Chicken broth
Unsalted butter, melted
Cream of chicken soup
Sour cream
Cream cheese, softened
Celery, diced
Yellow onion, diced
Garlic, minced
Frozen mixed vegetables or frozen peas (optional)
Garlic powder
Onion powder
Dried thyme
Salt
Black pepper
Fresh parsley, chopped (optional)

Directions

Preheat the oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish.
In a skillet over medium heat, sauté the onion and celery for 4–5 minutes until softened.
Add the garlic and cook for about 30 seconds until fragrant.
In a large bowl, combine the cream of chicken soup, sour cream, cream cheese, garlic powder, onion powder, thyme, salt, and black pepper until smooth.
Stir in the cooked chicken, sautéed vegetables, and frozen vegetables if using.
Spread the chicken mixture evenly into the prepared baking dish.
In a separate bowl, combine the stuffing mix, melted butter, and chicken broth until the stuffing is lightly moistened.
Spoon the stuffing evenly over the chicken mixture without pressing it down.
Cover the baking dish with foil and bake for 25 minutes.
Remove the foil and continue baking for 15–20 minutes, or until the stuffing is golden brown and the casserole is hot and bubbly.
Let the casserole rest for 5–10 minutes before serving.
Garnish with chopped fresh parsley if desired.

Servings and timing

Servings: 6–8
Prep time: 15 minutes
Cook time: 45 minutes
Rest time: 10 minutes
Total time: 1 hour 10 minutes

Variations

Use rotisserie chicken for an even quicker meal.
Add broccoli, green beans, mushrooms, or spinach for extra vegetables.
Mix shredded cheddar, Swiss, or mozzarella cheese into the filling.
Replace the cream of chicken soup with cream of mushroom or cream of celery soup.
Add cooked bacon for a smoky flavor.
Use leftover turkey instead of chicken after the holidays.
Stir in a teaspoon of poultry seasoning for extra savory flavor.
Top with crispy fried onions during the last 10 minutes of baking for added crunch.

Storage/Reheating

Store leftover Chicken and Stuffing Casserole in an airtight container in the refrigerator for up to 4 days. Reheat individual servings in the microwave or warm the casserole in a 350°F (175°C) oven until heated through. If the stuffing begins to dry out, add a small splash of chicken broth before reheating. Freeze the casserole before or after baking for up to 3 months. Thaw overnight in the refrigerator before reheating.

FAQs

Can I use rotisserie chicken?

Yes. Rotisserie chicken is one of the easiest and most flavorful options for this casserole.

Can I prepare this casserole ahead of time?

Absolutely. Assemble the casserole up to 24 hours in advance, cover, and refrigerate until ready to bake.

What stuffing mix works best?

Herb-seasoned boxed stuffing mix is the most popular choice, but homemade stuffing can also be used.

Can I add vegetables?

Yes. Broccoli, peas, carrots, green beans, mushrooms, spinach, and mixed vegetables all work wonderfully.

Can I use leftover turkey?

Yes. This recipe is an excellent way to use leftover holiday turkey.

How do I keep the stuffing from becoming dry?

Moisten the stuffing with broth before baking and avoid overbaking the casserole.

Can I freeze Chicken and Stuffing Casserole?

Yes. It freezes well for up to 3 months. For the best results, thaw overnight before reheating.

What side dishes pair well with this casserole?

Serve it with cranberry sauce, roasted vegetables, green beans, a fresh salad, mashed potatoes, or dinner rolls.

Can I substitute Greek yogurt for sour cream?

Yes. Plain Greek yogurt is an excellent substitute that maintains the casserole’s creamy texture.

Can I make this recipe gluten-free?

Yes. Use gluten-free stuffing mix and gluten-free condensed soup to easily adapt the recipe.

Conclusion

Chicken and Stuffing Casserole is the ultimate comfort food, combining tender chicken, a creamy savory filling, and a buttery herb stuffing topping into one hearty dish. Easy to prepare and perfect for family dinners, holidays, or meal prep, this timeless casserole is satisfying, versatile, and sure to become a regular favorite at your table.

Chicken and Stuffing Casserole

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Chicken and Stuffing Casserole is a comforting classic made with tender chicken, a creamy savory filling, and a buttery herb-seasoned stuffing topping baked until golden brown. It’s an easy family-friendly meal that’s perfect for weeknight dinners, holidays, or meal prep.

Author: Laura
Prep Time: 15 minutes
Cook Time: 45 minutes
Total Time: 1 hour 10 minutes
Yield: 6-8 servings
Category: Main Course
Method: Bake
Cuisine: American
Diet: Halal

Instructions

Preheat the oven to 350°F (175°C) and lightly grease a 9×13-inch baking dish.
In a skillet over medium heat, cook the onion and celery for 4–5 minutes until softened. Add the garlic and cook for 30 seconds.
In a large bowl, combine the cream of chicken soup, sour cream, cream cheese, garlic powder, onion powder, dried thyme, salt, and black pepper until smooth.
Stir in the cooked chicken, sautéed vegetables, and frozen vegetables if using.
Spread the chicken mixture evenly into the prepared baking dish.
In a separate bowl, combine the stuffing mix, melted butter, and chicken broth until lightly moistened.
Spoon the stuffing evenly over the chicken mixture without pressing it down.
Cover with foil and bake for 25 minutes.
Remove the foil and continue baking for 15–20 minutes, or until the stuffing is golden brown and the casserole is hot and bubbly.
Let the casserole rest for 5–10 minutes before serving.
Garnish with fresh parsley if desired.

Notes

Use rotisserie chicken or leftover turkey for a quick variation.
Add broccoli, green beans, mushrooms, spinach, or extra mixed vegetables for more nutrition.
Mix shredded cheddar, Swiss, or mozzarella cheese into the filling for extra richness.
Store leftovers in the refrigerator for up to 4 days or freeze for up to 3 months.
If reheating, add a splash of chicken broth if the stuffing seems dry.

Nutrition

Serving Size: 1 serving
Calories: 510 kcal
Sugar: 4 g
Sodium: 980 mg
Fat: 27 g
Saturated Fat: 11 g
Unsaturated Fat: 13 g
Trans Fat: 0.5 g
Carbohydrates: 31 g
Fiber: 2 g
Protein: 35 g
Cholesterol: 105 mg