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Artichoke and Spinach Chicken Casserole

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Artichoke and Spinach Chicken Casserole is a creamy, cheesy, and savory baked dish that combines tender chicken with a rich spinach-artichoke sauce. Inspired by the classic dip, this low-carb comfort meal delivers restaurant-quality flavor in an easy, family-friendly recipe perfect for weeknights or entertaining.

Ingredients

  • 4 boneless, skinless chicken breasts or thighs
  • 1 (10 oz) package frozen spinach, thawed and drained (or 4 cups fresh spinach, chopped and wilted)
  • 1 (14 oz) can artichoke hearts, drained and chopped
  • 8 oz cream cheese, softened
  • 1/2 cup sour cream or Greek yogurt
  • 1/4 cup mayonnaise
  • 1 cup shredded mozzarella cheese, divided
  • 1/4 cup grated Parmesan cheese
  • 2 cloves garlic, minced
  • 1/2 tsp onion powder
  • 1/2 tsp salt
  • 1/4 tsp black pepper
  • 1/4 tsp red pepper flakes (optional)
  • 1 tbsp olive oil or butter (for greasing)

Instructions

  1. Preheat oven to 375°F (190°C) and lightly grease a 9×13-inch baking dish with olive oil or butter.
  2. Season chicken with salt and pepper, then arrange in a single layer in the prepared baking dish.
  3. In a medium bowl, mix together cream cheese, sour cream, mayonnaise, garlic, onion powder, Parmesan, and half the mozzarella until smooth and creamy.
  4. Stir in the chopped spinach and artichoke hearts until evenly combined.
  5. Spread the spinach-artichoke mixture evenly over the chicken, then top with the remaining mozzarella cheese.
  6. Bake uncovered for 30–35 minutes, or until the chicken is cooked through (165°F/74°C) and the top is bubbly and golden.
  7. Let rest for 5 minutes before serving. Garnish with extra Parmesan or parsley if desired.

Notes

  • Use rotisserie or cooked chicken for a faster version—mix it directly with the sauce and bake for 20 minutes.
  • For extra flavor, add sun-dried tomatoes or sautéed mushrooms.
  • To make it dairy-free, use vegan cream cheese and non-dairy cheese alternatives.
  • Pairs well with rice, pasta, or a light salad.

Nutrition

Find it online: https://thefamilycooking.com/artichoke-and-spinach-chicken-casserole/